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Literature summary for 3.4.21.96 extracted from

  • Bruinenberg, P.G.; Doesburg, P.; Alting, A.C.; Exterkate, F.A.; de Vos, W.M.; Siezen, R.J.
    Evidence for a large dispensable segment in the subtilisin-like catalytic domain of the Lactococcus lactis cell-envelope proteinase (1994), Protein Eng., 7, 991-996.
    View publication on PubMed
Search for more literature for 3.4.21.96

Cloned(Commentary)

Cloned (Comment) Organism
-
 Lactococcus lactis

Protein Variants

Protein Variants Comment Organism
additional information in strain SK11 deletion of the largest loop, a fragment of amino acids 238-388 yields a mutant with a 2fold reduced activity Lactococcus lactis

Localization

Localization Comment Organism GeneOntology No. Textmining
cell envelope
-
 Lactococcus lactis 30313
-

Organism

Organism UniProt Comment Textmining
Lactococcus lactis
-
 SK11
-
Lactococcus lactis SK11
-
 SK11
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
alphas1-Casein + H2O
-
 Lactococcus lactis Fragments of alphas1-casein
-
 ?
alphas1-Casein + H2O
-
 Lactococcus lactis SK11 Fragments of alphas1-casein
-
 ?
alphas1-Casein fragment 1-23 + H2O the wild-type enzyme of strain SK11, cleaves bonds 16-17 and 17-18, the mutant enzyme lacking the loop 238-388 is highly specific for bond 21-22 Lactococcus lactis Fragments of alphas1-casein fragment 1-23
-
 ?
alphas1-Casein fragment 1-23 + H2O the wild-type enzyme of strain SK11, cleaves bonds 16-17 and 17-18, the mutant enzyme lacking the loop 238-388 is highly specific for bond 21-22 Lactococcus lactis SK11 Fragments of alphas1-casein fragment 1-23
-
 ?
beta-Casein + H2O
-
 Lactococcus lactis Fragments of beta-casein
-
 ?
beta-Casein + H2O
-
 Lactococcus lactis SK11 Fragments of beta-casein
-
 ?