Literature summary for 3.4.21.92 extracted from

de Bruijn, I.; Raaijmakers, J.M.
Regulation of cyclic lipopeptide biosynthesis in Pseudomonas fluorescens by the ClpP protease (2009), J. Bacteriol., 191, 1910-1923.

Search for more literature for 3.4.21.92

Cloned(Commentary)

Cloned (Comment)	Organism
Escherichia coli DH5alpha transformed with a pEX18Tc-clpP or a pME6031-clpP plasmid by heat shock transformation	Pseudomonas fluorescens

Protein Variants

Protein Variants	Comment	Organism
additional information	transcription of luxR(mA) is significantly repressed in the clpP mutant, and introduction of luxR(mA) restored, in part, massetolide biosynthesis and swarming motility of the clpP mutant. Addition of casamino acids enhances the transcription of luxR(mA) and massABC in the clpP mutant, leading to a partial rescue of massetolide production and swarming motility	Pseudomonas fluorescens

Organism

Organism	UniProt	Comment	Textmining
Pseudomonas fluorescens	B7TX39	SS101	-
Pseudomonas fluorescens SS101	B7TX39	SS101	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	ClpP affects the expression of luxR(mA), the transcriptional regulator of the massetolide biosynthesis genes massABC, thereby regulating biofilm formation and swarming motility of Pseudomonas fluorescens SS101. At the transcriptional level, ClpP-mediated regulation of massetolide biosynthesis operates independently of regulation by the GacA/GacS two-component system	Pseudomonas fluorescens	?	-	?
additional information	ClpP affects the expression of luxR(mA), the transcriptional regulator of the massetolide biosynthesis genes massABC, thereby regulating biofilm formation and swarming motility of Pseudomonas fluorescens SS101. At the transcriptional level, ClpP-mediated regulation of massetolide biosynthesis operates independently of regulation by the GacA/GacS two-component system	Pseudomonas fluorescens SS101	?	-	?

Synonyms

Synonyms	Comment	Organism
ClpP Protease	-	Pseudomonas fluorescens

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Release 2023.1 (January 2023)