Cloned (Comment) | Organism |
---|---|
Clp sequenced | Pseudomonas aeruginosa |
Clp sequenced | Rhodobacter capsulatus |
Clp sequenced | Enterococcus faecalis |
Clp sequenced | Streptococcus pyogenes |
Clp sequenced | Myxococcus xanthus |
Clp sequenced | Streptomyces coelicolor |
Clp sequenced | Helicobacter pylori |
Clp sequenced | Synechococcus sp. |
Clp sequenced | Clostridium acetobutylicum |
Clp sequenced | Porphyromonas gingivalis |
Clp sequenced | Bordetella pertussis |
Clp sequenced | Deinococcus radiodurans |
Clp sequenced | Listeria monocytogenes |
Clp sequenced | Chlorobaculum tepidum |
Clp sequenced | Shewanella putrefaciens |
Clp sequenced | Chlamydomonas reinhardtii |
Clp sequenced | Chlorella vulgaris |
Clp sequenced | Epifagus virginiana |
Clp sequenced | Haemophilus influenzae |
Clp sequenced | Lactococcus lactis |
Clp sequenced | Marchantia polymorpha |
Clp sequenced | Bacillus subtilis |
Clp sequenced | Nicotiana tabacum |
Clp sequenced | Oryza sativa |
Clp sequenced | Paracoccus denitrificans |
Clp sequenced | Pinus contorta |
Clp sequenced | Pinus thunbergii |
Clp sequenced | Streptococcus salivarius |
Clp sequenced | Borreliella burgdorferi |
Clp sequenced | Treponema pallidum |
Clp sequenced | Triticum aestivum |
Clp sequenced | Yersinia enterocolitica |
Clp sequenced | Zea mays |
Clp sequenced | Caulobacter vibrioides |
Clp sequenced | Chlamydia trachomatis |
Clp sequenced | Chlamydomonas moewusii |
Clp sequenced | Aquifex aeolicus |
Clp sequenced, nuclear encoded gene | Arabidopsis thaliana |
Clp sequenced, nuclear encoded gene | Populus tremula |
Clp sequenced, nuclear encoded gene | Fritillaria agrestis |
Clp sequenced, nuclear encoded gene | Homo sapiens |
Clp sequenced, nuclear encoded gene | Solanum lycopersicum |
Clp sequenced, nuclear encoded gene | Mus musculus |
Clp sequenced, nuclear encoded gene | Caenorhabditis elegans |
Clp sequenced, plastid encoded gene | Cyanophora paradoxa |
clpP gene detected | Salmonella enterica subsp. enterica serovar Typhimurium |
Crystallization (Comment) | Organism |
---|---|
- |
Escherichia coli |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Populus tremula | 5739 | - |
mitochondrion | - |
Homo sapiens | 5739 | - |
mitochondrion | - |
Mus musculus | 5739 | - |
mitochondrion | - |
Caenorhabditis elegans | 5739 | - |
plastid | - |
Chlorella vulgaris | 9536 | - |
plastid | - |
Epifagus virginiana | 9536 | - |
plastid | - |
Fritillaria agrestis | 9536 | - |
plastid | - |
Solanum lycopersicum | 9536 | - |
plastid | - |
Marchantia polymorpha | 9536 | - |
plastid | - |
Nicotiana tabacum | 9536 | - |
plastid | - |
Oryza sativa | 9536 | - |
plastid | - |
Pinus contorta | 9536 | - |
plastid | - |
Pinus thunbergii | 9536 | - |
plastid | - |
Triticum aestivum | 9536 | - |
plastid | - |
Zea mays | 9536 | - |
plastid | - |
Chlamydomonas moewusii | 9536 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | ClpA degrades large proteins down to short peptides of 7 to 10 amino acids, the process requires both Mg2+ and ATP hydrolysis | Escherichia coli |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Bacillus subtilis | ClpP linked to many activities, including sporulation, cell competence, stress tolerance and regulation of gene expression | ? | - |
? | |
additional information | Escherichia coli | removing of irreversibly damaged polypeptides | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Aquifex aeolicus | O67357 | - |
- |
Arabidopsis thaliana | P56772 | - |
- |
Arabidopsis thaliana | Q787X4 | - |
- |
Bacillus subtilis | P80244 | - |
- |
Bordetella pertussis | - |
- |
- |
Borreliella burgdorferi | O51698 | - |
- |
Caenorhabditis elegans | Q27539 | - |
- |
Caulobacter vibrioides | B8GX16 | - |
- |
Chlamydia trachomatis | P38002 | - |
- |
Chlamydomonas moewusii | P42379 | - |
- |
Chlamydomonas reinhardtii | P42380 | - |
- |
Chlorella vulgaris | P56317 | - |
- |
Chlorobaculum tepidum | - |
- |
- |
Clostridium acetobutylicum | - |
- |
- |
Cyanophora paradoxa | Q36863 | - |
- |
Deinococcus radiodurans | - |
- |
- |
Enterococcus faecalis | - |
- |
- |
Epifagus virginiana | P30063 | - |
- |
Escherichia coli | - |
- |
- |
Fritillaria agrestis | O49081 | - |
- |
Haemophilus influenzae | P43867 | - |
- |
Helicobacter pylori | - |
- |
- |
Homo sapiens | Q16740 | - |
- |
Lactococcus lactis | Q9ZAB0 | - |
- |
Listeria monocytogenes | - |
- |
- |
Marchantia polymorpha | P12208 | - |
- |
Mus musculus | O88696 | - |
- |
Mycobacterium tuberculosis | P9WPC5 and P9WPC3 | - |
- |
Mycobacterium tuberculosis H37Rv | P9WPC5 and P9WPC3 | - |
- |
Myxococcus xanthus | - |
- |
- |
Nicotiana tabacum | P12210 | tobacco | - |
Oryza sativa | P0C312 | rice | - |
Paracoccus denitrificans | P54414 | - |
- |
Pinus contorta | P36387 | - |
- |
Pinus thunbergii | P41609 | - |
- |
Populus tremula | - |
x tremuloides | - |
Porphyromonas gingivalis | - |
- |
- |
Pseudomonas aeruginosa | - |
- |
- |
Rhodobacter capsulatus | - |
- |
- |
Salmonella enterica subsp. enterica serovar Typhimurium | - |
- |
- |
Shewanella putrefaciens | - |
- |
- |
Solanum lycopersicum | Q42886 | - |
- |
Streptococcus pyogenes | - |
- |
- |
Streptococcus salivarius | P36398 | - |
- |
Streptomyces coelicolor | - |
- |
- |
Synechococcus sp. | - |
strain PCC 7942-3 | - |
Synechococcus sp. | O34125 | strain PCC 7942-2 | - |
Synechococcus sp. | P54415 | strain PCC 7942-1 | - |
Synechocystis sp. | P54416 | strain PCC 6803-1 | - |
Synechocystis sp. | P74467 | strain PCC 6803-3 | - |
Synechocystis sp. | Q59993 | strain PCC 6803-2 | - |
Treponema pallidum | O84003 | - |
- |
Triticum aestivum | P24064 | - |
- |
Yersinia enterocolitica | O30612 | - |
- |
Yersinia enterocolitica | Q60107 | - |
- |
Zea mays | P12340 | corn, maize | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | ClpP linked to many activities, including sporulation, cell competence, stress tolerance and regulation of gene expression | Bacillus subtilis | ? | - |
? | |
additional information | removing of irreversibly damaged polypeptides | Escherichia coli | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Clp protease | - |
Salmonella enterica subsp. enterica serovar Typhimurium |
Clp protease | - |
Escherichia coli |
Clp protease | - |
Pseudomonas aeruginosa |
Clp protease | - |
Rhodobacter capsulatus |
Clp protease | - |
Enterococcus faecalis |
Clp protease | - |
Streptococcus pyogenes |
Clp protease | - |
Myxococcus xanthus |
Clp protease | - |
Streptomyces coelicolor |
Clp protease | - |
Helicobacter pylori |
Clp protease | - |
Clostridium acetobutylicum |
Clp protease | - |
Porphyromonas gingivalis |
Clp protease | - |
Populus tremula |
Clp protease | - |
Bordetella pertussis |
Clp protease | - |
Deinococcus radiodurans |
Clp protease | - |
Listeria monocytogenes |
Clp protease | - |
Chlorobaculum tepidum |
Clp protease | - |
Shewanella putrefaciens |
Clp protease | - |
Chlamydomonas reinhardtii |
Clp protease | - |
Chlorella vulgaris |
Clp protease | - |
Cyanophora paradoxa |
Clp protease | - |
Epifagus virginiana |
Clp protease | - |
Fritillaria agrestis |
Clp protease | - |
Haemophilus influenzae |
Clp protease | - |
Homo sapiens |
Clp protease | - |
Lactococcus lactis |
Clp protease | - |
Solanum lycopersicum |
Clp protease | - |
Marchantia polymorpha |
Clp protease | - |
Mus musculus |
Clp protease | - |
Bacillus subtilis |
Clp protease | - |
Nicotiana tabacum |
Clp protease | - |
Oryza sativa |
Clp protease | - |
Paracoccus denitrificans |
Clp protease | - |
Pinus contorta |
Clp protease | - |
Pinus thunbergii |
Clp protease | - |
Streptococcus salivarius |
Clp protease | - |
Synechococcus sp. |
Clp protease | - |
Synechocystis sp. |
Clp protease | - |
Borreliella burgdorferi |
Clp protease | - |
Treponema pallidum |
Clp protease | - |
Triticum aestivum |
Clp protease | - |
Yersinia enterocolitica |
Clp protease | - |
Zea mays |
Clp protease | - |
Caenorhabditis elegans |
Clp protease | - |
Caulobacter vibrioides |
Clp protease | - |
Chlamydia trachomatis |
Clp protease | - |
Chlamydomonas moewusii |
Clp protease | - |
Arabidopsis thaliana |
Clp protease | - |
Mycobacterium tuberculosis |
Clp protease | - |
Aquifex aeolicus |
ClpC | - |
Listeria monocytogenes |
ClpQ | - |
Escherichia coli |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | ATP dependent, for full proteolytic activity ClpP must associate with one of two related ATPase subunits, ClpA or ClpX, other nucleoside triphosphates cannot substitute for ATP | Escherichia coli | |
ATP | ATP dependent, for full proteolytic activity ClpP must associate with one of two related ATPase subunits, ClpA or ClpX, other nucleoside triphosphates cannot substitute for ATP | Bacillus subtilis | |
ATP | ATP dependent, for full proteolytic activity ClpP must associate with one of two related ATPase subunits, ClpA or ClpX, other nucleoside triphosphates cannot substitute for ATP | Yersinia enterocolitica |