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Literature summary for 3.4.21.89 extracted from

  • Waite, R.D.; Rose, R.S.; Rangarajan, M.; Aduse-Opoku, J.; Hashim, A.; Curtis, M.A.
    Pseudomonas aeruginosa possesses two putative type I signal peptidases, LepB and PA1303, each with distinct roles in physiology and virulence (2012), J. Bacteriol., 194, 4521-4536.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
-
Pseudomonas aeruginosa

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
Pseudomonas aeruginosa 16020
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
20067
-
x * 20067, calculated Pseudomonas aeruginosa
32103
-
x * 32103, calculated Pseudomonas aeruginosa

Organism

Organism UniProt Comment Textmining
Pseudomonas aeruginosa Q9I441
-
-
Pseudomonas aeruginosa Q9I5G7
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Dabcyl-VSPAAFAADL(EDANS) + H2O signal peptide of elastase Pseudomonas aeruginosa ?
-
?

Subunits

Subunits Comment Organism
? x * 20067, calculated Pseudomonas aeruginosa
? x * 32103, calculated Pseudomonas aeruginosa

Synonyms

Synonyms Comment Organism
LepB
-
Pseudomonas aeruginosa
PA1303
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Pseudomonas aeruginosa

General Information

General Information Comment Organism
physiological function gene is essential for viability Pseudomonas aeruginosa
physiological function the gene is not essential for viability. Similar growth rates are observed for the PA1303 deletion mutant and the wild-type, and in stationary-phase cells no obvious changes in cell morphology are found. Chromosomal deletion mutation leads to the increased secretion of extracellular proteins, increased N-butanoyl homoserine lactone production and influences several quorum-sensing-controlled phenotypic traits, including swarming motility and the production of rhamnolipid and elastinolytic activity Pseudomonas aeruginosa