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Literature summary for 3.4.21.89 extracted from

  • Musial-Siwek, M.; Yeagle, P.L.; Kendall, D.A.
    A small subset of signal peptidase residues are perturbed by signal peptide binding (2008), Chem. Biol. Drug Des., 72, 140-146.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.21.89

Cloned(Commentary)

Cloned (Comment) Organism
doubly 13C, 15N- and singly 15N-isotopically labeled C-terminal SPase I DELTA2-75 expressed in Escherichia coli BL21(DE3) cells Escherichia coli

Localization

Localization Comment Organism GeneOntology No. Textmining
additional information a favorable interaction can occur between the hydrophobic surface of SPase I and the bacterial membrane Escherichia coli
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soluble
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 Escherichia coli
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-

Organism

Organism UniProt Comment Textmining
Escherichia coli
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-

Purification (Commentary)

Purification (Comment) Organism
doubly 13C, 15N- and singly 15N-isotopically labeled C-terminal SPase I DELTA2-75 Escherichia coli

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information substrate binding to SPase I proceeds consistent with induced-fit recognition. Residues Gln85, Ile86, Ser88, Gly89, Ser90, Met91, Leu95, Val132, Asp142, Ile144, and Lys145 in addition to Ile80, Glu82, Ile101, Gly109, and Lys134, are responsive to signal peptide binding and alter conformation Escherichia coli ?
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 ?

Synonyms

Synonyms Comment Organism
signal peptidase I
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 Escherichia coli
Spase I
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 Escherichia coli