Literature summary for 3.4.21.88 extracted from

Kamensek, S.; Podlesek, Z.; Gillor, O.; Zgur-Bertok, D.
Genes regulated by the Escherichia coli SOS repressor LexA exhibit heterogeneous expression (2010), BMC Microbiol., 10, 283.

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Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	-	-	-

General Information

General Information	Comment	Organism
physiological function	LexA regulated genes exhibit phenotypic heterogeneity as high level expression is observed in only a small subpopulation of cells. Heterogenous expression is established primarily by stochastic factors and the binding affinity of LexA to SOS boxes. In a lexA defective strain, high level expression of the regulated genes is observed in the large majority of the cells. The simultaneous expression of cka, encoding the pore forming colicin K, and lexA, investigated at the single cell level reveals high level expression of only cka in rare individual cells	Escherichia coli

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Release 2023.1 (January 2023)