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Literature summary for 3.4.21.88 extracted from
- SaPI operon I is required for SaPI packaging and is controlled by LexA (2007), Mol. Microbiol., 65, 41-50.
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| G94E | prevents cleavage of the LexA | Staphylococcus aureus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Staphylococcus aureus | - |
wild type and mutant containing G94E that prevents cleavage of the LexA | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| DNA + H2O | - |
Staphylococcus aureus | LexA-DNA complexes | detected by electrophoretical mobility shift assays, LexA repressor is the key regulatory protein of the DNA repair system, the SOS response. LexA is directly involved in SOS induction of the Staphylococcus aureus pathogenicity islands, SaPIs. LexA represses SaPI operon I containing ORF5, ORF7, 8 and 9 | ? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| LexA | - |
Staphylococcus aureus |
| LexA repressor | - |
Staphylococcus aureus |
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Release 2023.1 (January 2023)
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