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Literature summary for 3.4.21.79 extracted from

  • Kapelski, S.; de Almeida, M.; Fischer, R.; Barth, S.; Fendel, R.
    Antimalarial activity of granzyme B and its targeted delivery by a granzyme B-single-chain Fv fusion protein (2015), Antimicrob. Agents Chemother., 59, 669-672.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
pharmacology granzyme B has antimalarial activity against Plasmodium falciparum strain 3D7A of 1600 nM and can be targeted delivered by a granzyme B-single-chain Fv fusion protein, inhibitory activities on parasite growth of different fusion proteins on two different Plasmodium falciparum strains, overview Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P10144
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General Information

General Information Comment Organism
physiological function the enzyme granzyme B shows antimalarial activity Homo sapiens