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Literature summary for 3.4.21.79 extracted from

  • Darmon, A.J.; Nicholson, D.W.; Bleackley, C.
    Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B (1995), Nature, 377, 446-448.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens the enzyme cleaves and activates CPP32, the precursor of the protease responsible for cleavage of poly(ADPribose)polymerase ?
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Organism

Organism UniProt Comment Textmining
Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme cleaves and activates CPP32, the precursor of the protease responsible for cleavage of poly(ADPribose)polymerase Homo sapiens ?
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?
Protease CPP32 + H2O CPP32 is the precursor of the protease responsible for cleavage of poly(ADPribose)polymerase Homo sapiens ?
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?