Literature summary for 3.4.21.77 extracted from

Patane, S.; Marte, F.; Sturiale, M.
Prostate-specific antigen kallikrein complexes and acute myocardial infarction (2010), Int. J. Cardiol., 145, 227-228.

Search for more literature for 3.4.21.77

Inhibitors

Inhibitors	Comment	Organism	Structure
additional information	proteolytic activity of PSA is inhibited by the formation of irreversible complexes with serum protease inhibitors and other acute-phase proteins, such as alpha1-antichymotrypsin, alpha2-macroglobulin, inter-alpha1-trypsin inhibitor and alpha1-proteinase inhibitor	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
blood	-	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
prostate-specific antigen kallikrein	-	Homo sapiens
PSA	-	Homo sapiens

General Information

General Information	Comment	Organism
malfunction	diminished PSA during acute myocardial infarction and correlation of variation of PSA with coronary lesions and occurrence of major adverse cardiac events. Formation of irreversible PSA complexes (reflected by increased bound PSA) has significant correlation with high-sensitivity C-reactive protein	Homo sapiens
physiological function	increased PSA serum levels during prolonged cardiopulmonary resuscitation, cardiac surgery, extracorporeal cardiopulmonary bypass, cardiogenic shock due to acute myocardial infarction and acute myocardial infarction	Homo sapiens

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)