Literature summary for 3.4.21.77 extracted from

Kim, S.; Lee, J.B.; Lee, G.K.; Chang, J.
Vaccination with recombinant adenoviruses and dendritic cells expressing prostate-specific antigens is effective in eliciting CTL and suppresses tumor growth in the experimental prostate cancer (2009), Prostate, 69, 938-948.

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Application

Application	Comment	Organism
drug development	STEAP is a good immunologic target antigen against prostate cancer and vaccination regimen successfully elicits anti-tumor CTL responses and suppresses tumor growth	Homo sapiens

Cloned(Commentary)

Cloned (Comment)	Organism
male C57BL/6 mice injected with recombinant adenoviruses containing rAd/PSMA, rAd/PSCA and rAd/STEAP	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	PSMA, PSCA and STEAP are specifically upregulated in the transgenic murine prostate cancer. Significant numbers of STEAP-specific CD8 T cells in the peripheral blood and the spleen of immune mice using MHC I tetramers	Homo sapiens	?	-	?

Synonyms

Synonyms	Comment	Organism
prostate stem cell antigen	-	Homo sapiens
Prostate-specific membrane antigen	-	Homo sapiens
PSCA	-	Homo sapiens
PSMA	-	Homo sapiens
six-transmembrane epithelial antigen of the prostate	-	Homo sapiens
STEAP	-	Homo sapiens

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Release 2023.1 (January 2023)