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Literature summary for 3.4.21.77 extracted from

  • Christensson, A.; Laurell, C.B.; Lilja, H.
    Enzymatic activity of prostate-specific antigen and its reactions with extracellular serine proteinase inhibitors (1990), Eur. J. Biochem., 194, 755-763.
    View publication on PubMed
Search for more literature for 3.4.21.77

Inhibitors

Inhibitors Comment Organism Structure
alpha1-Aantichymotrypsin
-
 Homo sapiens
alpha2-Macroglobulin
-
 Homo sapiens
Pregnancy-zone protein
-
 Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.3
-
 Lys-Val-Tyr 4-nitroanilide
-
 Homo sapiens
1.7
-
 Arg-Pro-Tyr 4-nitroanilide
-
 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
one third of the purified protein is enzymatically inactive, due to carboxy-terminal cleavage of Lys145 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
semen
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Arg-Pro-Tyr 4-nitroanilide + H2O
-
 Homo sapiens Arg-Pro-Tyr + 4-nitroaniline
-
 ?
Lys-Val-Tyr 4-nitroanilide + H2O
-
 Homo sapiens Lys-Val-Tyr + 4-nitroaniline
-
 ?
semenogelin + H2O
-
 Homo sapiens semenogelin fragments
-
 ?

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.022
-
 Lys-Val-Tyr 4-nitroanilide
-
 Homo sapiens
0.028
-
 Arg-Pro-Tyr 4-nitroanilide
-
 Homo sapiens