Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.21.75 extracted from

  • Carney, T.J.; Feitosa, N.M.; Sonntag, C.; Slanchev, K.; Kluger, J.; Kiyozumi, D.; Gebauer, J.M.; Coffin Talbot, J.; Kimmel, C.B.; Sekiguchi, K.; Wagener, R.; Schwarz, H.; Ingham, P.W.; Hammerschmidt, M.
    Genetic analysis of fin development in zebrafish identifies furin and hemicentin1 as potential novel fraser syndrome disease genes (2010), PLoS Genet., 6, e1000907.
    View publication on PubMedView publication on EuropePMC

Protein Variants

Protein Variants Comment Organism
additional information the zebrafish craniofacial mutant sturgeon in the proprotein convertase FurinA displays mild blisters in the median fin folds Danio rerio

Organism

Organism UniProt Comment Textmining
Danio rerio
-
gene furina
-

Source Tissue

Source Tissue Comment Organism Textmining
embryo
-
Danio rerio
-
fin basement membrane Danio rerio
-

Synonyms

Synonyms Comment Organism
FurinA
-
Danio rerio

General Information

General Information Comment Organism
physiological function proprotein convertase FurinA plays a role in zebrafish fin development and cell surface shedding of Fras1 and Frem2, large basement membrane proteins, thereby allowing proper localization of the proteins within the basement membrane of forming fins, mechanisms of basement membrane anchorage, overview Danio rerio