Cloned (Comment) | Organism |
---|---|
293T cells transfected with furin | Mus musculus |
Protein Variants | Comment | Organism |
---|---|---|
additional information | deletion of the cysteine-rich domain and the cytoplasmic tail of furin does not abolish binding to cripto | Mus musculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-Bromopalmitate | inhibits nodal processing by Flag-tagged furin | Mus musculus | |
brefeldin A | inhibits the secretion of furin | Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | cytoplasmic tail | Mus musculus | 5737 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
embryo | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
nodal + H2O | cripto interacts with the nodal pro segment and mature domain and presents uncleaved precursor to extracellular furin that is recruited through its P-domain | Mus musculus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Proprotein convertase | - |
Mus musculus |