Application | Comment | Organism |
---|---|---|
medicine | inhibiting furin-like proprotein convertases protects the host from the distinct furin-dependent infections and lay a foundation for novel, host cell-focused therapies against acute diseases | Mus musculus |
medicine | inhibiting furin-like proprotein convertases protects the host from the distinct furin-dependent infections and lay a foundation for novel, host cell-focused therapies against acute diseases | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
recombinant furin prepared in the S2 Drosophila expression system | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
decanoyl-Arg-Val-Lys-Arg-chloromethylketone | - |
Homo sapiens | |
TPQRARRRKKRF | - |
Homo sapiens | |
TPQRARRRKKRT | - |
Homo sapiens | |
TPQRARRRKKRW | - |
Homo sapiens | |
TPQRARRRKKRY | - |
Homo sapiens | |
TPRARRRKKRG | - |
Homo sapiens | |
TPRARRRKKRI | - |
Homo sapiens | |
TPRARRRKKRT | - |
Homo sapiens | |
TPRARRRKKRT | - |
Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Mus musculus | - |
C57/BL6 mice | - |
Mus musculus C57BL/6 | - |
C57/BL6 mice | - |
Purification (Comment) | Organism |
---|---|
to homogeneity | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
hemagglutinin + H2O | - |
Homo sapiens | ? | - |
? | |
PA83 + H2O | - |
Homo sapiens | PA63 + PA20 | - |
? | |
Pseudomonas exotoxin A + H2O | - |
Mus musculus | ? | - |
? | |
Pseudomonas exotoxin A + H2O | - |
Homo sapiens | ? | - |
? | |
Pseudomonas exotoxin A + H2O | - |
Mus musculus C57BL/6 | ? | - |
? | |
pyroglutamic acid-Arg-Thr-Lys-Arg-methylcoumaryl-7-amide + H2O | - |
Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Proprotein convertase | - |
Mus musculus |
Proprotein convertase | - |
Homo sapiens |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.000023 | - |
TPRARRRKKRT | - |
Homo sapiens | |
0.00003 | - |
TPRARRRKKRI | - |
Homo sapiens | |
0.000033 | - |
TPQRARRRKKRT | - |
Homo sapiens | |
0.000034 | - |
TPQRARRRKKRW | - |
Homo sapiens | |
0.000038 | - |
TPQRARRRKKRF | - |
Homo sapiens | |
0.000047 | - |
TPQRARRRKKRY | - |
Homo sapiens | |
0.000057 | - |
TPRARRRKKRG | - |
Homo sapiens |