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Literature summary for 3.4.21.75 extracted from
- The C-terminal region of the proprotein convertase 1/3 (PC1/3) exerts a bimodal regulation of the enzyme activity in vitro (2007), FEBS J., 274, 3482-3491.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| recombinant soluble C-terminus truncated furin expressed in Sf9 insect cells | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| PC1/3 C-terminal peptide + H2O | cleavage by furin into a peptide with an apparent molecular mass of 12.5 kDa. Cleavage of the C-terminal to the pair of Args occupying positions 627 and 628 | Homo sapiens | ? | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Proprotein convertase | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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