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Literature summary for 3.4.21.75 extracted from

  • Dahlen, J.R.; Jean, F.; Thomas, G.; Foster, D.C.; Kisiel, W.
    Inhibition of soluble recombinant furin by human proteinase inhibitor 8 (1998), J. Biol. Chem., 273, 1851-1854.
    View publication on PubMed
Search for more literature for 3.4.21.75

Inhibitors

Inhibitors Comment Organism Structure
human proteinase inhibitor 8
-
 Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0032
-
 Pyr-Arg-Thr-Lys-Arg-4-methylcoumaryl-7-amide pH 7.5, 37°C Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens proteolytic processing of a variety of proteins in the exocytic and endocytic pathways ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
 human
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information proteolytic processing of a variety of proteins in the exocytic and endocytic pathways Homo sapiens ?
-
 ?
Pyr-Arg-Thr-Lys-Arg-4-methylcoumaryl-7-amide + H2O pERTKR-MCA Homo sapiens 7-amino-4-methylcoumarin + Pyr-Arg-Thr-Lys-Arg
-
 ?

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.0000000538
-
 human proteinase inhibitor 8 pH 7.5, 37°C Homo sapiens