Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
52000 | - |
x * 52000, SDS-PAGE | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
plasminogen + H2O | Mus musculus | - |
plasmin + ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Mus musculus | - |
BV-2 cell | a murine microglial cell line | Mus musculus | - |
microglia | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
plasminogen + H2O | - |
Mus musculus | plasmin + ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 52000, SDS-PAGE | Mus musculus |
Synonyms | Comment | Organism |
---|---|---|
uPA | - |
Mus musculus |
Urokinase-type plasminogen activator | - |
Mus musculus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Mus musculus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.6 | - |
assay at | Mus musculus |
Organism | Comment | Expression |
---|---|---|
Mus musculus | uPA is induced by ATP in microglia. The expression and release of uPA is under active regulation in BV2 microglial cells | up |
General Information | Comment | Organism |
---|---|---|
additional information | the expression and release of uPA is under active regulation in BV2 microglial cells | Mus musculus |
physiological function | urokinase-type plasminogen activator induces BV-2 microglial cell migration through activation of matrix metalloproteinase-9 | Mus musculus |