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BRENDA support

Literature summary for 3.4.21.73 extracted from

  • Gandhari, M.; Arens, N.; Majety, M.; Dorn-Beineke, A.; Hildenbrand, R.
    Urokinase-type plasminogen activator induces proliferation in breast cancer cells (2006), Int. J. Oncol., 28, 1463-1470.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
additional information reduction of enzyme expression by 53% by stable transfection with antisense/vector construct and by 65% by siRNa transfection results in strong decrease of cellular proliferation activity. Exogenous addition of high-molecular-weight enzyme or enzyme N-terminal fragment lead to increased cell proliferation Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
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Source Tissue

Source Tissue Comment Organism Textmining
MDA-MB-231 cell breast cancer cell Homo sapiens
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