Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
25700 | - |
x * 48800, A-chain, + x * 25700, B-chain, equilibrium sedimentation after cleavage of a single disulfide bond in Lys-plasminogen | Homo sapiens |
48800 | - |
x * 48800, A-chain, + x * 25700, B-chain, equilibrium sedimentation after cleavage of a single disulfide bond in Lys-plasminogen | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Oryctolagus cuniculus | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
proteolytic modification | activation of plasminogen by cleavage of a sensitive Arg-Val peptide bond in the COOH-terminal portion of Glu-plasminogen to give the two-chain plasmin molecule, followed by the cleavage of a Lys-Lys peptide bond in the NH2-terminal portion of the molecule. The latter event results in the release of a peptide, or peptides | Homo sapiens |
proteolytic modification | zymogen: plasminogen | Homo sapiens |
proteolytic modification | zymogen: plasminogen | Oryctolagus cuniculus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
plasma | - |
Homo sapiens | - |
serum | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Fibrin + H2O | - |
Homo sapiens | ? | - |
? | |
Fibrin + H2O | - |
Oryctolagus cuniculus | ? | - |
? | |
plasminogen + H2O | - |
Homo sapiens | ? | - |
? | |
plasminogen + H2O | - |
Oryctolagus cuniculus | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
monomer | - |
Oryctolagus cuniculus |
monomer | x * 48800, A-chain, + x * 25700, B-chain, equilibrium sedimentation after cleavage of a single disulfide bond in Lys-plasminogen | Homo sapiens |