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Literature summary for 3.4.21.7 extracted from

  • Gohda, K.; Teno, N.; Wanaka, K.; Tsuda, Y.
    Predicting subsite interactions of plasmin with substrates and inhibitors through computational docking analysis (2012), J. Enzyme Inhib. Med. Chem., 27, 571-577.
    View publication on PubMed
Search for more literature for 3.4.21.7

Activating Compound

Activating Compound Comment Organism Structure
tissue plasminogen activator
-
 Homo sapiens
urokinase plasminogen activator1
-
 Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
D-Ile-Phe-Lys
-
 Homo sapiens
L-Ile-Phe-Lys
-
 Homo sapiens
PKSI-527
-
 Homo sapiens
Tra-Tyr(O-Pic)-CONH-(C6H6)-(CH2)4-CH3
-
 Homo sapiens
Tra-Tyr(O-Pic)-CONH-(C6H6)-CH2-CH3
-
 Homo sapiens
Tra-Tyr(O-Pic)-CONH-(CH2)2-CH(CH3)-CH3
-
 Homo sapiens
Tra-Tyr(O-Pic)-CONH-(CH2)7-COOH
-
 Homo sapiens
Tra-Tyr(O-Pic)-CONH-(CH2)7-NH2
-
 Homo sapiens
YO-2 i.e. Tra-Tyr(O-Pic)-CONH-(CH2)7-CH3 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P00747
-
-

Synonyms

Synonyms Comment Organism
mu-plasmin serine protease domain of plasmin Homo sapiens

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.00053
-
 pH and temperature not specified in the publication Homo sapiens YO-2
0.00054
-
 pH and temperature not specified in the publication Homo sapiens Tra-Tyr(O-Pic)-CONH-(C6H6)-(CH2)4-CH3
0.0017
-
 pH and temperature not specified in the publication Homo sapiens Tra-Tyr(O-Pic)-CONH-(C6H6)-CH2-CH3
0.0019
-
 pH and temperature not specified in the publication Homo sapiens Tra-Tyr(O-Pic)-CONH-(CH2)2-CH(CH3)-CH3
0.0038
-
 pH and temperature not specified in the publication Homo sapiens Tra-Tyr(O-Pic)-CONH-(CH2)7-NH2
0.0055
-
 pH and temperature not specified in the publication Homo sapiens Tra-Tyr(O-Pic)-CONH-(CH2)7-COOH
0.02
-
 pH and temperature not specified in the publication Homo sapiens D-Ile-Phe-Lys
0.33
-
 pH and temperature not specified in the publication Homo sapiens L-Ile-Phe-Lys
0.63
-
 pH and temperature not specified in the publication Homo sapiens PKSI-527