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Literature summary for 3.4.21.7 extracted from

  • Miah, M.F.; Boffa, M.B.
    Functional analysis of mutant variants of thrombin-activatable fibrinolysis inhibitor resistant to activation by thrombin or plasmin (2009), J. Thromb. Haemost., 7, 665-672.
    View publication on PubMed

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.005
-
thrombin-activatable fibrinolysis inhibitor
-
Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information protein context, as well as the identity of amino acids at protease cleavage sites, dictate protease specificity Homo sapiens ?
-
?
thrombin-activatable fibrinolysis inhibitor + H2O mutant variants with variants in the amino acids surrounding the scissile R92-A93 bond such as P91S, R92K, and S90P exhibit specific impairment of activation by plasmin Homo sapiens ?
-
?

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.00042
-
thrombin-activatable fibrinolysis inhibitor
-
Homo sapiens