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Literature summary for 3.4.21.7 extracted from

  • Hervio, L.S.; Coombs, G.S.; Bergstrom, R.C.; Trivedi, K.; Corey, D.R.; Madison, E.L.
    Negative selectivity and the evolution of protease cascades: the specificity of plasmin for peptide and protein substrates (2000), Chem. Biol., 7, 443-453.
    View publication on PubMed
Search for more literature for 3.4.21.7

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.002
-
 GIYRSR pH 8.0 Homo sapiens
0.003
-
 AIYRSR pH 8.0 Homo sapiens
0.004
-
 CIYRSR pH 8.0 Homo sapiens
0.0047
-
 GPGRVV pH 8.0 Homo sapiens
0.0058
-
 GIYRSR pH 8.0 Homo sapiens
0.012
-
 GIVRSR pH 8.0 Homo sapiens
0.036
-
 SPGRVV pH 8.0 Homo sapiens
0.1
-
 LGGSGIYRSRSLE pH 8.0 Homo sapiens
0.21
-
 LGGSGYKIGGSLE pH 8.0 Homo sapiens
0.42
-
 LGGSGAVYKAGLE pH 8.0 Homo sapiens
0.47
-
 LGGSGIYRVRSLE pH 8.0 Homo sapiens
0.75
-
 LGGSIRYKGKSLE pH 8.0 Homo sapiens
1.6
-
 LGGSAMSRMSSLE pH 8.0 Homo sapiens
1.7
-
 LGGSGPYRSRSLE pH 8.0 Homo sapiens
1.85
-
 LGGSGIGRSRSLE pH 8.0 Homo sapiens
2.4
-
 LGGSGANFRGKLE pH 8.0 Homo sapiens
2.9
-
 LGGSGTQRRLRLE pH 8.0 Homo sapiens
3.7
-
 LGGSGIYRSVSLE pH 8.0 Homo sapiens
5.1
-
 KKSPGRVVGGSVAH pH 8.0 Homo sapiens
6.8
-
 LGGSSIYRSRSLE pH 8.0 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
AIYRSR + H2O
-
 Homo sapiens AIYR + Ser-Arg
-
 ?
CIYRSR + H2O
-
 Homo sapiens CIYR + Ser-Arg
-
 ?
GIVRSR + H2O
-
 Homo sapiens GIVR + Ser-Arg
-
 ?
GIYRSR + H2O
-
 Homo sapiens GIYR + Ser-Arg
-
 ?
GPGRVV + H2O
-
 Homo sapiens GPGR + Val-Val
-
 ?
KKSPGRVVGGSVAH + H2O
-
 Homo sapiens KKSPGR + VVGGSVAH
-
 ?
LGGSAMSRMSSLE + H2O
-
 Homo sapiens LGGSAMSR + MSSLE
-
 ?
LGGSGANFRGKLE + H2O
-
 Homo sapiens LGGSGANFR + GKLE
-
 ?
LGGSGAVYKAGLE + H2O
-
 Homo sapiens LGGSGAVYK + AGLE
-
 ?
LGGSGIGRSRSLE + H2O
-
 Homo sapiens LGGSGIGR + SRSLE
-
 ?
LGGSGIYRSRSLE + H2O
-
 Homo sapiens LGGSGIYR + SRSLE
-
 ?
LGGSGIYRSVSLE + H2O
-
 Homo sapiens LGGSGIYR + SVSLE
-
 ?
LGGSGIYRVRSLE + H2O
-
 Homo sapiens LGGSGIYR + VRSLE
-
 ?
LGGSGPYRSRSLE + H2O
-
 Homo sapiens LGGSGPYR + SRSLE
-
 ?
LGGSGTQRRLRLE + H2O
-
 Homo sapiens LGGSGTQR + RLRLE
-
 ?
LGGSGYKIGGSLE + H2O
-
 Homo sapiens LGGSGYK + IGGSLE
-
 ?
LGGSIRYKGKSLE + H2O
-
 Homo sapiens LGGSIRYK + GKSLE
-
 ?
LGGSSIYRSRSLE + H2O
-
 Homo sapiens LGGSSIYR + SRSLE
-
 ?
SPGRVV + H2O
-
 Homo sapiens SPGR + Val-Val
-
 ?

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.0016
-
 GPGRVV pH 8.0 Homo sapiens
0.0086
-
 KKSPGRVVGGSVAH pH 8.0 Homo sapiens
0.036
-
 AIYRSR pH 8.0 Homo sapiens
0.039
-
 GIVRSR pH 8.0 Homo sapiens
0.039
-
 SPGRVV pH 8.0 Homo sapiens
0.6
-
 GIYRSR pH 8.0 Homo sapiens
1.5
-
 GIYRSR pH 8.0 Homo sapiens
2.7
-
 CIYRSR pH 8.0 Homo sapiens
3.2
-
 LGGSAMSRMSSLE pH 8.0 Homo sapiens
12
-
 LGGSGTQRRLRLE pH 8.0 Homo sapiens
12
-
 LGGSGYKIGGSLE pH 8.0 Homo sapiens
16
-
 LGGSGIYRVRSLE pH 8.0 Homo sapiens
35
-
 LGGSSIYRSRSLE pH 8.0 Homo sapiens
39
-
 LGGSGIYRSVSLE pH 8.0 Homo sapiens
40
-
 LGGSGAVYKAGLE pH 8.0 Homo sapiens
44
-
 LGGSIRYKGKSLE pH 8.0 Homo sapiens
53
-
 LGGSGIGRSRSLE pH 8.0 Homo sapiens
68
-
 LGGSGANFRGKLE pH 8.0 Homo sapiens
92
-
 LGGSGPYRSRSLE pH 8.0 Homo sapiens
120
-
 LGGSGIYRSRSLE pH 8.0 Homo sapiens