Literature summary for 3.4.21.69 extracted from

Bakoush, O.; Ohlin, A.K.; Strandberg, K.; Kurkus, J.
Low plasma activated protein C-protein C inhibitor complex concentration is associated with vascular access failure in hemodialysis patients (2008), Nephron. Clin. Pract., 110, c151-c157.

Search for more literature for 3.4.21.69

Activating Compound

Activating Compound	Comment	Organism	Structure
additional information	concentration of the APC-protein C inhibitor complex is increased in hypercoagulable states and is therefore a sensitive indicator of the degree of activation of blood coagulation	Homo sapiens

Application

Application	Comment	Organism
medicine	a low level of APC-protein C inhibitor complex in plasma may be associated with an increased risk of arteriovenous fistula/graft failure in hemodialysis patients	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
Protein C inhibitor	inactivates	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
blood	-	Homo sapiens	-
plasma	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	patients with frequent arteriovenous fistula/graft failures have a significantly lower level of APC-protein C inhibitor complex in plasma than those with less frequent arteriovenous fistula/graft failures	Homo sapiens	?	-	?

Synonyms

Synonyms	Comment	Organism
Activated protein C	-	Homo sapiens
APC	-	Homo sapiens

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Release 2023.1 (January 2023)