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Literature summary for 3.4.21.69 extracted from

  • Gennari, L.C.; Blanco, A.N.; Dominguez, M.P.; Grosso, S.H.; Lazzari, M.A.
    Endogenous or exogenous coagulation factor level and the response to activated protein C (2006), Thromb. Res., 118, 269-273.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
active factor VIIIa + H2O Homo sapiens the inactivation of factor VIIIa by the enzyme is responsible for its high anticoagulation effect, high factor VIII contents lead to increased resistance to activated protein C, while factor II and factor X are not correleted to active protein C resistance, mechanism, overview inactive factor VIII + domain B
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Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
active factor VIIIa + H2O proteolytic inactivation Homo sapiens inactive factor VIII + domain B
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?
active factor VIIIa + H2O the inactivation of factor VIIIa by the enzyme is responsible for its high anticoagulation effect, high factor VIII contents lead to increased resistance to activated protein C, while factor II and factor X are not correleted to active protein C resistance, mechanism, overview Homo sapiens inactive factor VIII + domain B
-
?

Synonyms

Synonyms Comment Organism
Activated protein C
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Homo sapiens
APC
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Homo sapiens