Cloned (Comment) | Organism |
---|---|
- |
Homo sapiens |
- |
Bos taurus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | contains gamma-carboxyglutamic acid residues required for Ca2+-dependent membrane binding | Homo sapiens | |
Ca2+ | contains gamma-carboxyglutamic acid residues required for Ca2+-dependent membrane binding | Bos taurus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | role of protein C in the regulation of blood coagulation | ? | - |
? | |
additional information | Bos taurus | role of protein C in the regulation of blood coagulation | ? | - |
? | |
additional information | Homo sapiens | activated protein C complexes with protein S on the surface of either platelets or the endothelium, these complexes catalyze the proteolytic inactivation of factors Va and VIIIa | ? | - |
? | |
additional information | Bos taurus | activated protein C complexes with protein S on the surface of either platelets or the endothelium, these complexes catalyze the proteolytic inactivation of factors Va and VIIIa | ? | - |
? | |
additional information | Homo sapiens | the enzyme is one of the gamma-carboxyglutamic acid-containing coagulation factors. It is formed by protein C, the proenzyme that circulates in plasma, by the action of a complex of thrombin with thrombomodulin or by serine endopeptidases present in several snake venoms | ? | - |
? | |
additional information | Bos taurus | the enzyme is one of the gamma-carboxyglutamic acid-containing coagulation factors. It is formed by protein C, the proenzyme that circulates in plasma, by the action of a complex of thrombin with thrombomodulin or by serine endopeptidases present in several snake venoms | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
plasma | - |
Homo sapiens | - |
plasma | - |
Bos taurus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Factor Va + H2O | - |
Homo sapiens | ? | - |
? | |
Factor Va + H2O | - |
Bos taurus | ? | - |
? | |
Factor VIIIa + H2O | - |
Homo sapiens | ? | - |
? | |
Factor VIIIa + H2O | - |
Bos taurus | ? | - |
? | |
additional information | role of protein C in the regulation of blood coagulation | Homo sapiens | ? | - |
? | |
additional information | role of protein C in the regulation of blood coagulation | Bos taurus | ? | - |
? | |
additional information | activated protein C complexes with protein S on the surface of either platelets or the endothelium, these complexes catalyze the proteolytic inactivation of factors Va and VIIIa | Homo sapiens | ? | - |
? | |
additional information | activated protein C complexes with protein S on the surface of either platelets or the endothelium, these complexes catalyze the proteolytic inactivation of factors Va and VIIIa | Bos taurus | ? | - |
? | |
additional information | the enzyme is one of the gamma-carboxyglutamic acid-containing coagulation factors. It is formed by protein C, the proenzyme that circulates in plasma, by the action of a complex of thrombin with thrombomodulin or by serine endopeptidases present in several snake venoms | Homo sapiens | ? | - |
? | |
additional information | the enzyme is one of the gamma-carboxyglutamic acid-containing coagulation factors. It is formed by protein C, the proenzyme that circulates in plasma, by the action of a complex of thrombin with thrombomodulin or by serine endopeptidases present in several snake venoms | Bos taurus | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
More | in humans 40% of the protein S circulates free and 60% in a reversible complex with C4b binding protein | Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
vitamin K | enzyme is dependent on | Homo sapiens | |
vitamin K | enzyme is dependent on | Bos taurus |