A199S |
no effect on activity |
Parengyodontium album |
A236V |
lethal |
Parengyodontium album |
E138A |
lethal, increased stability of the serine protease subtilisin |
Parengyodontium album |
G293A |
strong positive effect on activity |
Parengyodontium album |
I132V |
positive effect on activity |
Parengyodontium album |
I310K |
no effect on activity, increased stability of the serine protease subtilisin |
Parengyodontium album |
K208H |
positive effect on activity |
Parengyodontium album |
K332R |
positive effect on activity |
Parengyodontium album |
L180I |
positive effect on activity |
Parengyodontium album |
L299C |
lethal, increased stability of the serine protease subtilisin |
Parengyodontium album |
M145F |
no effect on activity, increased stability of the serine protease subtilisin |
Parengyodontium album |
N95C |
lethal, increased stability of the serine protease subtilisin |
Parengyodontium album |
P265S |
no effect on activity, increased stability of the serine protease subtilisin |
Parengyodontium album |
P355S |
no effect on activity, increased stability of the serine protease subtilisin |
Parengyodontium album |
P97S |
lethal, increased stability of the serine protease subtilisin |
Parengyodontium album |
R237N |
no effect on activity |
Parengyodontium album |
S107D |
no effect on activity |
Parengyodontium album |
S123A |
positive effect on activity |
Parengyodontium album |
S273T |
positive effect on activity |
Parengyodontium album |
S337N |
positive effect on activity |
Parengyodontium album |
V167I |
no effect on activity |
Parengyodontium album |
V267I |
positive effect on activity |
Parengyodontium album |
Y151A |
strong positive effect on activity |
Parengyodontium album |
Y194S |
no effect on activity, random mutation obtained during synthesis of wild-type proteinase K |
Parengyodontium album |