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Literature summary for 3.4.21.64 extracted from

  • Morihara, K.; Tsuzuki, H.
    Specificity of proteinase K from Tritirachium album Limber for synthetic peptides (1975), Agric. Biol. Chem., 39, 1489-1492.
No PubMed abstract available
Search for more literature for 3.4.21.64

Inhibitors

Inhibitors Comment Organism Structure
Chloromethyl ketone derivatives e.g. carboxybenzoyl-Ala-Gly-PheCH2Cl, carboxybenzoyl-Ala-PheCH2Cl Parengyodontium album

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
 additional information
-
 Parengyodontium album
0.8
-
 acetyl-(Ala)2-Phe methyl ester
-
 Parengyodontium album
0.9
-
 carboxybenzoyl-(Ala)2-Lys methyl ester
-
 Parengyodontium album
1
-
 acetyl-(Ala)2-Ala methyl ester
-
 Parengyodontium album
3
-
 carboxybenzoyl-L-Ala-L-Lys methyl ester carboxybenzoyl-Phe-Lys methyl ester Parengyodontium album
3.3
-
 benzoyl-L-Arg ethyl ester
-
 Parengyodontium album
5.6
-
 acetyl-L-Trp ethyl ester
-
 Parengyodontium album
8.8
-
 Acetyl-Tyr ethyl ester
-
 Parengyodontium album
9
-
 carboxybenzoyl-Leu-Lys methyl ester
-
 Parengyodontium album
12
-
 acetyl-L-Phe ethyl ester
-
 Parengyodontium album
19
-
 carboxybenzoyl-Gly-Lys methyl ester
-
 Parengyodontium album
20
-
 carboxybenzoyl-D-Ala-Lys methyl ester
-
 Parengyodontium album
21
-
 carboxybenzoyl-L-Lys methyl ester
-
 Parengyodontium album
26
-
 acetyl-L-Val methyl ester
-
 Parengyodontium album
30
-
 acetyl-L-Leu methyl ester
-
 Parengyodontium album
45
-
 acetyl-L-Ala methyl ester
-
 Parengyodontium album

Organism

Organism UniProt Comment Textmining
Parengyodontium album
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
commercial preparation from Merck Parengyodontium album
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-(Ala)2-Ala methyl ester + H2O
-
 Parengyodontium album ?
-
 ?
acetyl-(Ala)2-Phe methyl ester + H2O
-
 Parengyodontium album ?
-
 ?
acetyl-L-Ala methyl ester + H2O
-
 Parengyodontium album acetyl-L-Ala + methanol
-
 ?
acetyl-L-Leu methyl ester + H2O
-
 Parengyodontium album acetyl-L-Leu + methanol
-
 ?
acetyl-L-Phe ethyl ester + H2O
-
 Parengyodontium album acetyl-L-Phe + ethanol
-
 ?
acetyl-L-Trp ethyl ester + H2O
-
 Parengyodontium album acetyl-L-Trp + ethanol
-
 ?
acetyl-L-Val methyl ester + H2O
-
 Parengyodontium album acetyl-L-Val + methanol
-
 ?
Acetyl-Tyr ethyl ester + H2O
-
 Parengyodontium album ?
-
 ?
Benzoyl-L-Arg ethyl ester + H2O
-
 Parengyodontium album Benzoyl-L-Arg + ethanol
-
 ?
carboxybenzoyl-(Ala)2-Lys methyl ester + H2O
-
 Parengyodontium album carboxybenzoyl-(Ala)2-Lys + methanol
-
 ?
carboxybenzoyl-D-Ala-L-Lys methyl ester + H2O
-
 Parengyodontium album carboxybenzoyl-D-Ala-L-Lys + methanol
-
 ?
carboxybenzoyl-Gly-Lys methyl ester + H2O
-
 Parengyodontium album carboxybenzoyl-Gly-Lys + methanol
-
 ?
carboxybenzoyl-L-Ala-L-Lys methyl ester + H2O
-
 Parengyodontium album carboxybenzoyl-L-Ala-L-Lys + methanol
-
 ?
carboxybenzoyl-L-Lys methyl ester + H2O
-
 Parengyodontium album carboxybenzoyl-L-Lys + methanol
-
 ?
carboxybenzoyl-Leu-Lys methyl ester + H2O
-
 Parengyodontium album carboxybenzoyl-Leu-Lys + methanol
-
 ?
additional information
-
 Parengyodontium album ?
-
 ?
N-Acetylated amino acid esters + H2O
-
 Parengyodontium album ?
-
 ?
N-Acetylated peptide esters + H2O
-
 Parengyodontium album ?
-
 ?
Synthetic peptide substrates + H2O primarily specific against aromatic or hydrophobic amino acid residues at the carboxyl side of the splitting point, activity is markedly promoted by elongating the peptide chain to the N-terminal from the splitting point Parengyodontium album ?
-
 ?