Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
extracellular | - |
Echis carinatus | - |
- |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Zn2+ | Zn-metalloprotease | Echis carinatus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
prothrombin + H2O | Echis carinatus | ecarin converts prothrombin to thrombin also if the prothrombin is not gamma-carboxylated | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Echis carinatus | Q90495 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
venom | - |
Echis carinatus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
prothrombin + H2O | ecarin converts prothrombin to thrombin also if the prothrombin is not gamma-carboxylated | Echis carinatus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ecarin | - |
Echis carinatus |
prothrombin activator | - |
Echis carinatus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Echis carinatus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.4 | - |
assay at | Echis carinatus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
additional information | ecarin is not dependent on any cofactors | Echis carinatus |
General Information | Comment | Organism |
---|---|---|
physiological function | apart from the natural activation pathway, human prothrombin can also be activated by prothrombin activators in snake venoms. Ecarin is not dependent on any cofactors, but generates meizothrombin | Echis carinatus |