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Literature summary for 3.4.21.6 extracted from

  • Pryzdial, E.L.G.; Kessler, G.E.
    Kinetics of blood coagulation factor Xaalpha autoproteolytic conversion to factor Xabeta. Effect on inhibition by antithrombin, prothrombinase assembly, and enzyme activity (1996), J. Biol. Chem., 271, 16621-16626.
    View publication on PubMed
Search for more literature for 3.4.21.6

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
prothrombin + H2O Bos taurus factor Xaalpha is predominantly responsible for thrombin generation. Slow conversion to factor Xabeta coordinates coagulation and the initiation of fibrinolysis at sites of thrombinase assembly ?
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Organism

Organism UniProt Comment Textmining
Bos taurus
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Posttranslational Modification

Posttranslational Modification Comment Organism
proteolytic modification autoproteolytic conversion of factor Xaalpha to factor Xabeta by excision of a 4000 Da fragment, beta-peptide Bos taurus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
prothrombin + H2O factor Xaalpha is predominantly responsible for thrombin generation. Slow conversion to factor Xabeta coordinates coagulation and the initiation of fibrinolysis at sites of thrombinase assembly Bos taurus ?
-
 ?