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Literature summary for 3.4.21.6 extracted from

  • Owen, W.G.; Esmon, C.T.; Jackson, C.M.
    The conversion of prothrombin to thrombin. I. Characterization of the reaction products formed during the activation of bovine prothrombin (1974), J. Biol. Chem., 249, 594-605.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
Factor V required for hydrolysis of prothrombin Bos taurus
Phospholipid required for hydrolysis of prothrombin Bos taurus

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
prothrombin + H2O
-
Bos taurus thrombin + ? thrombin and two activation fragments ?