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Literature summary for 3.4.21.6 extracted from

  • Roser-Jones, C.; Becker, R.C.
    Apixaban: an emerging oral factor Xa inhibitor (2010), J. Thromb. Thrombolysis, 29, 141-146.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
apixaban a direct, oral applicable, selective factor Xa inhibitor and activated prothrombinase, reversible and potent inhibition of both free and cell bound factor Xa. It has low potential for drug-drug interactions and is predominantly eliminated through metabolic pathways and non-renal mechanisms Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Synonyms

Synonyms Comment Organism
factor Xa
-
Homo sapiens

General Information

General Information Comment Organism
physiological function factor Xa is part of the blood coagulation cascade Homo sapiens