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Literature summary for 3.4.21.6 extracted from
- Novel anticoagulants in clinical development: focus on factor Xa and direct thrombin inhibitors (2009), J. Cardiovasc. Med., 10, 616-623.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| apixaban | a direct oral factor Xa inhibitor | Homo sapiens |  |
| bivalirudin | intravenously applicated inhibitor | Homo sapiens | |
| fondaparinux | an indirect factor Xa inhibitor | Homo sapiens | |
| idrabiotaparinux | i.e. SSR126517E, an indirect factor Xa inhibitor | Homo sapiens | |
| idraparinux | an indirect factor Xa inhibitor | Homo sapiens | |
| lepiprudin | - |
Homo sapiens | |
| additional information | factor Xa acts as anticoagulants, clinical studies, overview | Homo sapiens | |
| rivaroxaban | a direct oral factor Xa inhibitor | Homo sapiens | |
| warfarin | - |
Homo sapiens | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| prothrombin + H2O | Homo sapiens | - |
thrombin + ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| prothrombin + H2O | - |
Homo sapiens | thrombin + ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| factor Xa | - |
Homo sapiens |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | factor Xa is part of the blood coagulation cascade | Homo sapiens |
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