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Literature summary for 3.4.21.6 extracted from
- Activation of antithrombin as a factor IXa and Xa inhibitor involves mitigation of repression rather than positive enhancement (2009), FEBS Lett., 583, 3397-3400.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| antithrombin | allosteric activation of antithrombin as a factor IXa and Xa inhibitor requires binding of a high-affinity heparin pentasaccharide and involves mitigation of repression rather than positive enhancement, via a mechanism in which heparin activates antithrombin by mitigating an unfavorable surface interaction, by altering its nature, and by moving the attached proteinase away from the site of the unfavorable interaction through RCL expulsion, detailed overview | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| factor Xa | - |
Homo sapiens |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | factor Xa is part of the blood coagulation cascade | Homo sapiens |
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