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Literature summary for 3.4.21.6 extracted from

  • Calatzis, A.; Peetz, D.; Haas, S.; Spannagl, M.; Rudin, K.; Wilmer, M.
    Prothrombinase-induced clotting time assay for determination of the anticoagulant effects of unfractionated and low-molecular-weight heparins, fondaparinux, and thrombin inhibitors (2008), Am. J. Clin. Pathol., 130, 446-454.
    View publication on PubMed

Application

Application Comment Organism
analysis development of an assay for the monitoring of anticoagulants inhibiting factor Xa and/or factor IIa. Assay is based on the addition of factor Xa and snake venom RVV-V, i.e. Russell viper venom factor V activator specifically activating factor V and phospholipids to platelet-poor plasma. Assay shows an almost linear dose-response and high sensitivity for unfractionated heparin, low molecular weight heparins, r-hirudin, and argatroban Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
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Source Tissue

Source Tissue Comment Organism Textmining
blood plasma
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Homo sapiens
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