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Literature summary for 3.4.21.59 extracted from

  • Zhang, S.; Zeng, X.; Yang, H.; Hu, G.; He, S.
    Mast cell tryptase induces microglia activation via protease-activated receptor 2 signaling (2012), Cell. Physiol. Biochem., 29, 931-940.
    View publication on PubMed
Search for more literature for 3.4.21.59

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
pro-interleukin-6 + H2O Rattus norvegicus
-
 interleukin-6 + ?
-
 ?
pro-nuclear factor-kappa B + H2O Rattus norvegicus
-
 nuclear factor-kappa B + ?
-
 ?
pro-tissue necrosis factor + H2O Rattus norvegicus
-
 tissue necrosis factor + ?
-
 ?
protease-activated receptor 2 + H2O Rattus norvegicus
-
 fibrin + ?
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
mast cell
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
pro-interleukin-6 + H2O
-
 Rattus norvegicus interleukin-6 + ?
-
 ?
pro-nuclear factor-kappa B + H2O
-
 Rattus norvegicus nuclear factor-kappa B + ?
-
 ?
pro-tissue necrosis factor + H2O
-
 Rattus norvegicus tissue necrosis factor + ?
-
 ?
protease-activated receptor 2 + H2O
-
 Rattus norvegicus fibrin + ?
-
 ?

Synonyms

Synonyms Comment Organism
Mast cell tryptase
-
 Rattus norvegicus

General Information

General Information Comment Organism
physiological function mast cell tryptase induces microglia activation via protease-activated receptor 2-mitogen-activated protein kinase-nuclear factor kappa B signaling pathway, which will contribute to the development of microglia-mediated inflammation in brain Rattus norvegicus