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Literature summary for 3.4.21.59 extracted from

  • Kaieda, S.; Shin, K.; Nigrovic, P.A.; Seki, K.; Lee, R.T.; Stevens, R.L.; Lee, D.M.
    Synovial fibroblasts promote the expression and granule accumulation of tryptase via interleukin-33 and its receptor ST-2 (IL1RL1) (2010), J. Biol. Chem., 285, 21478-21486.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.21.59

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasmic vesicle
-
 Mus musculus 31410
-

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
mast cell
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
D-phenylalanyl-pipecolyl-L-arginine-4-nitroanilide + H2O
-
 Mus musculus D-phenylalanyl-pipecolyl-L-arginine + 4-nitroaniline
-
 ?

Synonyms

Synonyms Comment Organism
mast cell protease-6
-
 Mus musculus
Mast cell tryptase
-
 Mus musculus
MC protease-6
-
 Mus musculus
MCP-6
-
 Mus musculus
tryptase-beta
-
 Mus musculus

Expression

Organism Comment Expression
Mus musculus mast cells from IL1RL1-null mice exhibit a marked reduction in MCP-6 expression down
Mus musculus mast cells lacking IL1RL1 exhibit defective fibroblast-driven tryptase accumulation up