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Literature summary for 3.4.21.59 extracted from

  • Schwartz, L.B.; Bradford, T.R.
    Regulation of tryptase from human lung mast cells by heparin. Stabilization of the active tetramer (1986), J. Biol. Chem., 261, 7372-7379.
    View publication on PubMed

General Stability

General Stability Organism
heparin glycosaminoglycan stabilizes, maximal stabilization at a weight ratio to tryptase equal to or greater than unity Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
diisopropyl fluorophosphate
-
Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
33000
-
2 * 34000 + 2 * 33000, human, SDS-PAGE of DFP-inhibited enzyme Homo sapiens
34000
-
2 * 34000 + 2 * 33000, human, SDS-PAGE of DFP-inhibited enzyme Homo sapiens
132000
-
human, gel filtration Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
lung
-
Homo sapiens
-
mast cell
-
Homo sapiens
-

Subunits

Subunits Comment Organism
tetramer 2 * 34000 + 2 * 33000, human, SDS-PAGE of DFP-inhibited enzyme Homo sapiens