Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
hydrolysis of proteins in presence of ATP | binding of ATP induces a conformational change that facilitates the coupling of nucleotide hydrolysis with peptide substrate delivery to the peptidase activs site | Escherichia coli |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | kcat-value of peptide cleavage decreases with the reduction in the nucleotide binding affinity in the following order: ATP, CTP, GTP, UTP. Both nucleotide binding and hydrolysis contribute to peptidase turnover | Escherichia coli |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | binding of ATP induces a conformational change that facilitates the coupling of nucleotide hydrolysis with peptide substrate delivery to the peptidase active site | Escherichia coli |