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Literature summary for 3.4.21.53 extracted from
- The energy utilized in protein breakdown by the ATP-dependent protease (La) from Escherichia coli (1987), J. Biol. Chem., 262, 722-726.
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | requirement | Escherichia coli |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
carrying lon-gene on plasmid pJMC40 | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| casein + H2O | methylcasein | Escherichia coli | hydrolyzed casein | - |
? | |
| casein + H2O | guanidinated casein | Escherichia coli | hydrolyzed casein | - |
? | |
| Denatured bovine serum albumin + H2O | - |
Escherichia coli | ? | - |
? | |
| Globin + H2O | beta-globin | Escherichia coli | ? | - |
? | |
| Glucagon + H2O | - |
Escherichia coli | Hydrolyzed glucagon | - |
? | |
| Parathyroid hormone + H2O | - |
Escherichia coli | ? | - |
? | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
assay at | Escherichia coli |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| ATP | two ATP molecules are hydrolyzed for each peptide bond cleaved in proteins | Escherichia coli | |
| ATP | ATP-dependent protease | Escherichia coli | |
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Release 2023.1 (January 2023)
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