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Literature summary for 3.4.21.5 extracted from

  • Walfridsson, H.; Johansson, B.; Englund, A.; Kennebaeck, G.; Schwieler, J.; Kongstad, O.; Wahlander, K.; Malm, A.R.; Edvardsson, N.
    Effects of AZD0837, a novel direct thrombin inhibitor, on the electrophysiological properties of the human heart: a randomized, double-blind, parallel-group, placebo-controlled study (2010), Clin. Drug Investig., 30, 461-471.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
AR-H067637 selective direct thrombin inhibitor, AZD0837 is bioconverted to its active form AR-H067637 Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
fibrinogen + H2O Homo sapiens
-
fibrin + fibrinopeptide A + fibrinopeptide B
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
blood plasma
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
fibrinogen + H2O
-
Homo sapiens fibrin + fibrinopeptide A + fibrinopeptide B
-
?