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Literature summary for 3.4.21.5 extracted from

  • Rock, G.; Neurath, D.; Semple, E.; Harvey, M.; Freedman, M.
    Preparation and characterization of human thrombin for use in a fibrin glue (2007), Transfus. Med., 17, 187-191.
    View publication on PubMed
Search for more literature for 3.4.21.5

Application

Application Comment Organism
biotechnology usage of human thrombin in a fibrin glue, method development, thrombin initiates clotting and cross-linking of fibrin from cryoprecipitate to produce an entirely autologous fibrin glue, overview Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
37000
-
 x * 37000, SDS-PAGE Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
fibrinogen + H2O Homo sapiens
-
 fibrin + ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
native enzyme from plasma Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
plasma
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
 activity of the plasma enzyme is within the range of 54-75 IU/ml Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
fibrinogen + H2O
-
 Homo sapiens fibrin + ?
-
 ?

Subunits

Subunits Comment Organism
? x * 37000, SDS-PAGE Homo sapiens