Inhibitors | Comment | Organism | Structure |
---|---|---|---|
CH-248 | i.e. (R)-cyclohexylalanyl-Pro-Arg[CH2OCH2CF3] | Homo sapiens | |
inogatran | i.e. carboxymethyl-(R)-cyclohexylalanyl-L-piperidine-2-carboxylic acid noragmatine | Homo sapiens | |
melagatran | i.e. carboxymethyl-(R)-cyclohexylglycine-L-azetidine-2-carboxylic acid 4-amidinobenzylamine | Homo sapiens | |
additional information | inhibitor binding mechanism and kinetics | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | kinetics | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-phenylalanyl-pipecolyl-L-arginine-4-nitroanilide + H2O | i.e. S2238, synthetic chromogenic substrate | Homo sapiens | D-phenylalanyl-pipecolyl-L-arginine + 4-nitroaniline | - |
? |
Synonyms | Comment | Organism |
---|---|---|
alpha-thrombin | - |
Homo sapiens |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | kinetics at 25°C and 37°C, thermodynamic analysis of inhibitor binding and interaction | Homo sapiens | |
0.0000013 | - |
melagatran | pH 7.4, 25°C | Homo sapiens | |
0.000003 | - |
CH-248 | pH 7.4, 25°C | Homo sapiens | |
0.0000043 | - |
inogatran | pH 7.4, 25°C | Homo sapiens |