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Literature summary for 3.4.21.47 extracted from

  • Lutz, H.U.; Fumia, S.; Schurtenberger, C.; Alaia, V.
    Opinion paper: Stimulation of complement amplification or activation of the alternative pathway of complement? (2007), Mol. Immunol., 44, 3862-3865.
    View publication on PubMed
Search for more literature for 3.4.21.47

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
complement component C3 + H2O Homo sapiens
-
 complement component C3a + complement component C3b
-
 ?
complement component C5 + H2O Homo sapiens
-
 complement component C5a + complement component C5b
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens P00751
-
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
 central role of the amplification loop in complement activation discussed, development of a model placing the amplification loop at the center of the complement system as a means to expand complement component C3/C5 activation and irrespective of the origin of the triggering complement component C3b molecules Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
complement component C3 + H2O
-
 Homo sapiens complement component C3a + complement component C3b
-
 ?
complement component C3 + H2O potencies of the amplification loop of the alternative complement pathway summarized Homo sapiens complement component C3a + complement component C3b
-
 ?
complement component C5 + H2O
-
 Homo sapiens complement component C5a + complement component C5b
-
 ?

Synonyms

Synonyms Comment Organism
C3 convertase
-
 Homo sapiens