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Literature summary for 3.4.21.46 extracted from

  • Hu, J.; Ye, H.; Fu, A; Chen, X.; Wang, Y.; Chen, X.; Ye, X.; Xiao, W.; Duan, X.; Wei, Y.; Chen, L.
    Deguelin-an inhibitor to tumor lymphangiogenesis and lymphatic metastasis by down-regulation of vascular endothelial cell growth factor-D in lung tumor model (2010), Int. J. Cancer, 127, 2455-2466.
    View publication on PubMed

Application

Application Comment Organism
medicine by downregulation of VEGF-D expression in a lung tumor mouse model using Deguielin, a rotenoid of the flavonoid family, tumor-associated lymphangiogenesis and lymphatic metastasis are suppressed Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
-

Synonyms

Synonyms Comment Organism
VEGF-D
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Homo sapiens

Expression

Organism Comment Expression
Homo sapiens deguelin, a rotenoid of the flavonoid family, significantly down-regulates the expression of VEGF-D both at the mRNA and protein level in VEGF-D transfected LL/2 Lewis lung cells down