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Literature summary for 3.4.21.46 extracted from

  • Reid, K.B.M.; Johnson, D.M.A.; Gagnon, J.; Prohaska, R.
    Preparation of human factor D of the alternative pathway of complement (1981), Methods Enzymol., 80, 134-143.
    View publication on PubMed
Search for more literature for 3.4.21.46

General Stability

General Stability Organism
freezing and thawing causes approximately 30% loss of activity Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
diisopropyl fluorophosphate
-
 Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens the enzyme is a component of the alternative pathway of human complement ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
 assay methods Homo sapiens

Storage Stability

Storage Stability Organism
-70°C, no aggregation occurs, stable Homo sapiens
4°C, 0.1 M Tris-HCl, 0.2 M NaCl, 2 mM EDTA, pH 8.0, 0.02% w/v NaN3, several months, about 10% loss of activity Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
factor B + H2O cleavage at a single Arg-Lys bond Homo sapiens Bb fragment + Ba fragment
-
 ?
additional information the enzyme is a component of the alternative pathway of human complement Homo sapiens ?
-
 ?