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Literature summary for 3.4.21.43 extracted from

  • Roumenina, L.T.; Jablonski, M.; Hue, C.; Blouin, J.; Dimitrov, J.D.; Dragon-Durey, M.A.; Cayla, M.; Fridman, W.H.; Macher, M.A.; Ribes, D.; Moulonguet, L.; Rostaing, L.; Satchell, S.C.; Mathieson, P.W.; Sautes-Fridman, C.; Loirat, C.; Regnier, C.H.; Halbwachs-Mecarelli, L.; Fremeaux-Bacchi, V.
    Hyperfunctional C3 convertase leads to complement deposition on endothelial cells and contributes to atypical hemolytic uremic syndrome (2009), Blood, 114, 2837-2845.
    View publication on PubMed
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General Stability

General Stability Organism
the C3 convertase is stabilized by the binding of properdin Ovis aries

Organism

Organism UniProt Comment Textmining
Ovis aries
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
erythrocyte
-
 Ovis aries
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
complement component C3 + H2O
-
 Ovis aries complement component C3a + complement component C3b
-
 ?

Synonyms

Synonyms Comment Organism
C3bBb
-
 Ovis aries
classical pathway C3 convertase
-
 Ovis aries