Literature summary for 3.4.21.43 extracted from

Spitzer, D.; Mitchell, L.M.; Atkinson, J.P.; Hourcade, D.E.
Properdin can initiate complement activation by binding specific target surfaces and providing a platform for de novo convertase assembly (2007), J. Immunol., 179, 2600-2608.

Search for more literature for 3.4.21.43

Activating Compound

Activating Compound	Comment	Organism	Structure
additional information	properdin can initiate complement activation by binding specific target surfaces, e.g. microbial targets like Neisseria gonorrhoeae, and Escherichia coli and Salmonella typhimurium lipopolysaccharide mutants, or yeast cell walls, , and providing a platform for de novo convertase assembly and function via the alternative pathway, overview, recombinant human compound	Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
complement component C3 + H2O	Homo sapiens	-	complement component C3a + complement component C3b	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
complement component C3 + H2O	-	Homo sapiens	complement component C3a + complement component C3b	-	?

Synonyms

Synonyms	Comment	Organism
C3 convertase	-	Homo sapiens
C3bBbP	-	Homo sapiens

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)