Literature summary for 3.4.21.4 extracted from

Knecht, W.; Cottrell, G.S.; Amadesi, S.; Mohlin, J.; Skaregaerde, A.; Gedda, K.; Peterson, A.; Chapman, K.; Hollenberg, M.D.; Vergnolle, N.; Bunnett, N.W.
Trypsin IV or mesotrypsin and p23 cleave protease-activated receptors 1 and 2 to induce inflammation and hyperalgesia (2007), J. Biol. Chem., 282, 26089-26100.

Search for more literature for 3.4.21.4

Inhibitors

Inhibitors	Comment	Organism	Structure
additional information	resistant to soybean trypsin inhibitor and aprotinin	Homo sapiens
additional information	resistant to soybean trypsin inhibitor and aprotinin	Rattus norvegicus

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
24000	-	SDS-PAGE	Homo sapiens
24000	-	SDS-PAGE	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-
Rattus norvegicus	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
SP-Sepharose column chromatography	Homo sapiens
SP-Sepharose column chromatography	Rattus norvegicus

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
GDDSTPSILPAPRGYPGQV + H2O	-	Homo sapiens	GDDSTPSILPAPR + GYPGQV	-	?
GPNSKGRSLIGRLDTPYGGC + H2O	-	Rattus norvegicus	GPNSKGR + SLIGRLDTPYGGC	-	?
N-acetyl-GTNRSSKGRSLIGKVDGTSHVTGKGVT-amide + H2O	-	Homo sapiens	SLIGKVDGTSHVTGKGVT-amide + N-acetyl-GTNRSSKGR	-	?
NATLDPRSFLLRNPNDKYE + H2O	-	Homo sapiens	NATLDPR + SFLLRNPNDKYE	-	?
tosyl-GPK-p-nitroanilide + H2O	-	Homo sapiens	tosyl-GPK + p-nitroaniline	-	?
tosyl-GPK-p-nitroanilide + H2O	-	Rattus norvegicus	tosyl-GPK + p-nitroaniline	-	?
tosyl-GPR-p-nitroanilide + H2O	-	Homo sapiens	tosyl-GPR + p-nitroaniline	-	?
tosyl-GPR-p-nitroanilide + H2O	-	Rattus norvegicus	tosyl-GPR + p-nitroaniline	-	?

Synonyms

Synonyms	Comment	Organism
mesotrypsin	-	Homo sapiens
p23	-	Rattus norvegicus
pro23	-	Rattus norvegicus
trypsin IV	-	Homo sapiens

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)