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Literature summary for 3.4.21.39 extracted from

  • Sansoe, G.; Aragno, M.; Mastrocola, R.; Mengozzi, G.; Novo, E.; Parola, M.
    Role of chymase in the development of liver cirrhosis and its complications experimental and human data (2016), PLoS ONE, 11, e0162644 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.21.39

Inhibitors

Inhibitors Comment Organism Structure
SF2809E
-
 Homo sapiens
SF2809E
-
 Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
 Homo sapiens
-
kidney
-
 Rattus norvegicus
-
liver
-
 Homo sapiens
-
liver
-
 Rattus norvegicus
-

Expression

Organism Comment Expression
Rattus norvegicus in liver and kidneys of G3 rats there is a larger amount of chymase than in normal rats up
Homo sapiens the enzyme expression is increased after treatment with transforming growth factor-beta1 up

General Information

General Information Comment Organism
physiological function chymase, through synthesis of angiotensin II and other mediators, plays a role in the derangement of liver and kidney function in chronic liver diseases Homo sapiens
physiological function chymase, through synthesis of angiotensin II and other mediators, plays a role in the derangement of liver and kidney function in chronic liver diseases Rattus norvegicus